Enhanced descriptions from Syndetics:

This fascinating book presents a scientifically objective, and thoroughly documented exposition of the pharmacological and psychological effects of nearly every known substance that affects human consciousness, from alcohol to Zopiclone. It also features first-hand accounts and descriptions of the social, cultural, and religious milieus in which many psychotropic plants are used, and discusses historical allusions to many literary and scientific figures who used or wrote of mind-altering drugs, including Freud, Dickens, Yeats, and Huxley. Intended for a wide audience of general readers seeking unbiased information, the book gives an accessible explanation of drug-receptor interaction and organic chemical structures, as well as descriptions of the discovery, isolation, and syntheses of the chemical substances responsible for drug activity. Written by an experienced chemist, the book nevertheless keeps technical information to a minimum.

Table of contents provided by Syndetics

• Preface
• 1 Mind and Molecule: Neurotransmission in Context
• 2 Opium and the Opiods
• 3 Depressants: Alcohol, Benzodiazepines, Barbiturates
• 4 Stimulants: Nicotine, Caffeine, Cocaine, Amphetamines
• 5 Antipsychotics and Antidepressants
• 6 Psychedelics: LSD to XTC
• 7 Dissociatives and Cannabinoids: PCP, THC, ETCs
• 8 HONC: The Four Key Elements
• 9 Return to the Second Dimension
• 10 How Shall I Bond Thee? Let Me Count the Ways
• 11 Through the Looking-Glass
• Index

Reviews provided by Syndetics

CHOICE Review

By limiting his subject, Perrine has been able to present a more detailed description of drugs that affect the brain. The information is generally grouped according to pharmacological effect and chronological order within the group. Social issues involved with drug use are also discussed. In general, chemical structures are included along with at least a sentence or two describing the synthesis. Some basic cell biology and communication between cells are included to illustrate the mechanism of action of some of the drugs. Interesting opinions are included on teenage smoking, definition of addiction, falling asleep while driving, and misuse of amine stimulants. Detailed descriptions of the thoughts and dreams of persons under the influence of various hallucinogenic agents are especially interesting. There is a wealth of information on the discovery of many drugs and their pharmacologic activity. Well written and well referenced. An outstanding contribution to the field of medicinal chemistry and a genuine pleasure to read for anyone with an interest in drug activity, drug addiction, and drug chemistry. Highest recommendation. Upper-division undergraduates through professionals. A. M. Mattocks; University of North Carolina at Chapel Hill

Author notes provided by Syndetics

Daniel M. Perrine is at Associate Professor of Chemistry, Loyola College, MD.