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Manual of clinical laboratory immunology / Noel R. Rose ... [et al.].
By: Rose, Noel R
.
Contributor(s): Rose, Noel R | American Society for Microbiology.
Material type: 
BookPublisher: Washington, D.C. : American Society for Microbiology, 1992Edition: 4th ed.Description: 987p.ISBN: 1555810446; 9781555810443; 9781555810436.Subject(s): Immunodiagnosis -- Handbooks, manuals, etc | Immunologic techniques | Immunology | Immunology -- Handbooks, mauals, etc | Biology, life sciences | Reference works | Medical laboratory testing & techniques | ImmunologyDDC classification: 616.0756 ROS
| Item type | Current library | Call number | Copy number | Status | Barcode | |
|---|---|---|---|---|---|---|
| Reference | MTU Kerry North Campus Library Reference | 616.0756 ROS (Browse shelf(Opens below)) | 1 | Not for loan | 38888000334726 |
Total holds: 0
Enhanced descriptions from Syndetics:
Featuring the latest on standard and cutting-edge immunological tests and procedures in clinical laboratory immunology, the much-anticipated sixth edition of the Manual of Clinical Laboratory Immunology (MCLI) reflects the continued evolution of clinical immunology. Considered the "bible" of the clinical immunology laboratory, MCLI6 provides an up-to-date description of the methods used in the clinical laboratory for diagnosis and monitoring of immune-mediated and autoimmune diseases, transplantation rejection, and cancer. The best features of earlier editions have remained in this update, including a step-by-step interpretive approach to methodology, with emphasis on the practical issues and pitfalls in performing laboratory procedures, the appropriate indication, and the interpretation of results. Throrughly indexed and fully illustrated, this much-heralded reference has been called "a clear reflection of the practice of clinical laboratory immunology" (Current Microbiology).
Includes bibliographical references and indexes.
Table of contents provided by Syndetics
- Editorial Board (p. xiii)
- Contributors (p. xv)
- Preface (p. xxv)
- Part I General Methods (p. 1)
- Section A General Methods: Antibody-Based and Molecular (p. 3)
- 1 Introduction (p. 5)
- 2 Antibody-Based Methods (p. 6)
- 3 Introduction to Molecular Methodology (p. 26)
- 4 Specimen Collection and Handling (p. 49)
- Section B Immunoglobulin Methods (p. 51)
- 5 Introduction (p. 53)
- 6 Immunoglobulin Genes (p. 54)
- 7 Clinical Indications and Applications of Electrophoresis and Immunofixation (p. 66)
- 8 Immunochemical Characterization of Immunoglobulins (p. 71)
- 9 Immunoglobulin Quantification (p. 92)
- 10 Cryoglobulins, Cryofibrinogenemia, and Pyroglobulins (p. 97)
- Section C Complement (p. 107)
- 11 Introduction (p. 109)
- 12 Choosing Complement Tests: Differentiating between Hereditary and Acquired Deficiency (p. 111)
- 13 Molecular Genetic Analyses of Human Complement Components C4A and C4B (p. 117)
- Section D Flow Cytometric Analysis (p. 133)
- 14 Introduction (p. 135)
- 15 Immunophenotyping of Lymphocytes by Flow Cytometry (p. 137)
- 16 Immunophenotyping of Leukemia and Lymphoma by Flow Cytometry (p. 148)
- 17 Functional Assays by Flow Cytometry (p. 160)
- 18 DNA Content Flow Cytometry (p. 171)
- 19 Standardized Flow Cytometry Assays for Enumerating Hematopoietic Stem Progenitor Cells (p. 185)
- 20 Multiplexed Bead Assay in Flow Cytometry: Flow Cytometry-Based Suspension Array Technology (p. 197)
- Section E Cellular Immunology Assays (p. 209)
- 21 Introduction (p. 211)
- 22 Delayed-Type Hypersensitivity Skin Testing (p. 212)
- 23 Cryopreservation of Peripheral Blood Mononuclear Cells (p. 220)
- 24 T-Lymphocyte Activation and Cell Signaling (p. 224)
- 25 Methods for Detection of Antigen-Specific CD8[superscript +] T Cells and Assessment of Their Function (p. 238)
- 26 Evaluation of the T-Cell Receptor Repertoire (p. 244)
- 27 Molecular Diagnosis of Chronic Granulomatous Disease (p. 256)
- 28 Evaluation of Phagocytic Cell Function (p. 265)
- 29 Flow Cytometric Detection and Quantification of Apoptotic Cells (p. 274)
- 30 Non-Flow Cytometry-Based Cell Enumeration Systems (p. 284)
- 31 Quantification of Recent Thymic Emigrants: T-Cell-Receptor Excision Circles (p. 291)
- 32 Measurement of NK-Cell Activity in Humans (p. 296)
- 33 Cellular Immune Assays for Evaluation of Vaccine Efficacy in Developing Countries (p. 301)
- Section F Cytokines, Chemokines, and Adhesion Molecules (p. 318)
- 34 Introduction (p. 319)
- 35 Protein Analysis and Bioassays of Cytokines and Cytokine Receptors (p. 320)
- 36 Flow Cytometric Analysis of Cytokines (p. 338)
- 37 Molecular Analysis of Cytokines and Cytokine Receptors (p. 347)
- 38 Chemokine and Chemokine Receptor Analysis (p. 357)
- 39 Cell Adhesion Molecules: Potential Therapeutic and Diagnostic Implications (p. 368)
- Section G Immunohistology and Immunopathology (p. 378)
- 40 Introduction (p. 379)
- 41 Immunohistochemistry--Principles and Advances (p. 380)
- 42 Immunohistochemistry: Diagnostic and Prognostic Applications in Tumor Diagnosis (p. 387)
- 43 Immunofluorescence Methods in the Diagnosis of Skin and Renal Disease (p. 393)
- Part II Immunologic Diagnosis and Monitoring of Disease (p. 403)
- Section H Infectious Diseases Caused by Bacteria, Mycoplasmas, Chlamydiae, and Rickettsiae (p. 405)
- 44 Introduction (p. 407)
- 45 Immune Response to Streptococcal Antigens: Diagnostic Methods (p. 409)
- 46 Haemophilus influenzae Type b, Neisseria meningitidis, Streptococcus pneumoniae, and Corynebacterium diphtheriae Vaccines (p. 418)
- 47 Clostridium tetani: Immune Response and Diagnostic Methods (p. 432)
- 48 Immunologic Methods for Diagnosis of Infections by Gram-Negative Cocci (p. 435)
- 49 Immunologic Methods for Diagnosis of Infections Caused by Diarrheagenic Members of the Families Enterobacteriaceae and Vibrionaceae (p. 447)
- 50 Serodiagnosis of Helicobacter pylori Infection and Eradication (p. 462)
- 51 Detection of Antibodies to Legionella spp. (p. 468)
- 52 Immunologic Methods for Diagnosis of Spirochetal Diseases (p. 477)
- 53 Lyme Disease: Serodiagnosis of Borrelia burgdorferi Sensu Lato Infection (p. 494)
- 54 Immunological Tests in Tuberculosis and Leprosy (p. 502)
- 55 Nocardiae and Agents of Actinomycosis (p. 511)
- 56 Mycoplasma Infection: Immunologic and Molecular Biologic Diagnostic Techniques (p. 516)
- 57 Chlamydiae (p. 522)
- 58 Immunoserology of the Rickettsiales, Bartonella, and Coxiella (p. 528)
- Section I Mycotic and Parasitic Diseases (p. 543)
- 59 Introduction (p. 545)
- 60 Clinical Immunoparasitology (p. 547)
- 61 Clinical Immunomycology (p. 559)
- Section J Viral Diseases (p. 585)
- 62 Introduction (p. 587)
- 63 Rapid Viral Diagnosis (p. 588)
- 64 Antibody-Enhanced Detection of Viruses in Cell Cultures (p. 598)
- 65 Herpes Simplex Virus (p. 605)
- 66 Varicella-Zoster Virus (p. 611)
- 67 Epstein-Barr Virus (p. 615)
- 68 Cytomegalovirus (p. 627)
- 69 Human Herpesvirus 6, 7, and 8 (p. 635)
- 70 Papovaviruses (p. 646)
- 71 Adenoviruses (p. 652)
- 72 Parvovirus B19 (p. 659)
- 73 Influenza Viruses (p. 666)
- 74 Respiratory Syncytial Virus and the Parainfluenza Viruses (p. 672)
- 75 Measles and Mumps (p. 682)
- 76 Rubella Virus (p. 687)
- 77 Enteroviruses (p. 693)
- 78 Viral Hepatitis (p. 696)
- 79 Enzyme Immunoassays for Detection of Rotavirus Antigen and Antibody (p. 718)
- 80 Arboviruses (p. 727)
- 81 Hantaviruses (p. 736)
- 82 Rabies Virus (p. 742)
- 83 Human T-Cell Lymphotropic Virus Types I and II (p. 749)
- Section K Human Immunodeficiency Virus (p. 755)
- 84 Introduction (p. 757)
- 85 Immunologic Evaluation of Patients with Human Immunodeficiency Virus Infection (p. 758)
- 86 Quantitation of Viremia and Determination of Drug Resistance in Patients with Human Immunodeficiency Virus Infection (p. 772)
- 87 Principles and Procedures of Human Immunodeficiency Virus Serodiagnosis (p. 790)
- Section L Immunodeficiency Diseases (p. 805)
- 88 Introduction (p. 807)
- 89 Genetics of Inherited Immunodeficiency Diseases and Diagnostic Techniques (p. 810)
- 90 Combined B- and T-Cell Deficiencies (p. 819)
- 91 Investigation of Signal Transduction Defects (p. 826)
- 92 Primary Antibody Deficiencies in Children and Adults (p. 830)
- 93 Inherited and Acquired C1-Inhibitor Deficiency (p. 837)
- 94 Genetically Determined Deficiencies of the Complement System: C1, C4, C2, and C3 (p. 842)
- 95 Deficiencies of Mannose-Binding Lectin, the Alternative Pathway, and the Late Complement Components (p. 847)
- 96 Neutropenia and Neutrophil Defects (p. 855)
- Section M Allergic Diseases (p. 865)
- 97 Introduction (p. 867)
- 98 Quantitation and Standardization of Allergens (p. 868)
- 99 In Vivo Diagnostic Allergy Testing Methods (p. 875)
- 100 The Diagnostic Allergy Laboratory (p. 883)
- 101 Tests for Immunological Reactions to Drugs and Occupational Allergens (p. 891)
- 102 Assay Methods for Measurement of Mediators and Markers of Allergic Inflammation (p. 899)
- 103 Immunological Tests for Evaluation of Hypersensitivity Pneumonitis and Allergic Bronchopulmonary Aspergillosis (p. 910)
- Section N Systemic Autoimmune Diseases (p. 919)
- 104 Introduction (p. 921)
- 105 Immunofluorescent Antinuclear Antibody Tests (p. 922)
- 106 Autoantibody Testing by Non-Fluorescein Isothiocyanate (FITC) Methods (p. 933)
- 107 Enzyme-Linked Immunosorbent Assays for Diagnostically Important Antinuclear Antibodies (p. 951)
- 108 Rheumatoid Factors (p. 961)
- 109 Antiphospholipid Antibody Tests (p. 973)
- 110 Antineutrophil Cytoplasmic Antibodies (ANCAs) and ANCA Testing (p. 981)
- Section O Organ-Localized Autoimmune Diseases (p. 987)
- 111 Introduction (p. 989)
- 112 Endocrinopathies (p. 990)
- 113 Autoantibody Profiles of Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome (p. 1005)
- 114 Autoimmune Autonomic Neuropathy and Neuromuscular Hyperexcitability Disorders (p. 1013)
- 115 Autoantibodies to Glycolipids in Peripheral Neuropathy (p. 1018)
- 116 Detection of Antimitochondrial Autoantibodies in Primary Biliary Cirrhosis and Liver-Kidney Microsomal Antibodies in Autoimmune Hepatitis (p. 1023)
- 117 Skin Diseases (p. 1032)
- 118 Cardiovascular Diseases (p. 1043)
- 119 Kidney and Lung Disease Mediated by Anti-Glomerular Basement Membrane Antibodies: Detection by Western Blot Analysis (p. 1049)
- 120 Autoimmunity of Testis, Ovary, and Spermatozoa (p. 1054)
- 121 Immunologic Testing for Celiac Disease and Inflammatory Bowel Disease (p. 1060)
- 122 Autoimmune Thrombocytopenia (p. 1065)
- 123 Autoimmune Hemolytic Anemia (p. 1070)
- Section P Cancer (p. 1081)
- 124 Introduction (p. 1083)
- 125 Human Tumor Antigens Recognized by T Cells (p. 1085)
- 126 Cancer Vaccines (p. 1091)
- 127 Malignancies of the Lymphoid and Histiocytic Systems (p. 1098)
- 128 Monitoring of Immunologic Therapies (p. 1108)
- 129 The Future of Chip Technologies in Cancer Care and Research (p. 1118)
- Section Q Transplantation Immunology and Immunogenetics (p. 1125)
- 130 Immunogenetics: Transplantation and Beyond (p. 1127)
- 131 HLA Typing by Molecular Methods (p. 1134)
- 132 Evaluation of the Humoral Response in Transplantation (p. 1153)
- 133 Evaluation of the Cellular Immune Response in Transplantation (p. 1164)
- 134 Histocompatibility Assessment in Bone Marrow Transplantation (p. 1176)
- 135 Graft Engineering for Hematopoietic Stem Cell Transplantation (p. 1187)
- 136 Minor Histocompatibility Antigens (p. 1201)
- Part III Administration (p. 1209)
- Section R Laboratory Management (p. 1211)
- 137 Introduction (p. 1213)
- 138 Standardization of Immunoassay Methodologies (p. 1215)
- 139 Quality Assurance (p. 1227)
- 140 Planning Statistical Quality Control Procedures (p. 1239)
- 141 Clinical Significance and Cost-Effectiveness of Clinical Immunology Testing (p. 1251)
- 142 Clinical Immunology Laboratory Accreditation, Licensure, and Credentials (p. 1258)
- 143 Establishment and Verification of Reference Values (p. 1271)
- Author Index (p. 1283)
- Subject Index (p. 1285)