Enhanced descriptions from Syndetics:

Biochemistry 3rd edition DONALD VOET, University of Pennsylvania, USA and JUDITH G. VOET, Swarthmore College, USA Biochemistry is a modern classic that has been thoroughly revised. Don and Judy Voet explain biochemical concepts while offering a unified presentation of life and its variation through evolution. Incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge.
* This edition has been updated to reflect the enormous advances in molecular and protein structure
* Integrated Biochemical Interactions CD

Table of contents provided by Syndetics

• Part I Introduction and Background (p. 1)
• Chapter 1 Life (p. 3)
• 1. Prokaryotes (p. 3)
• 2. Eukaryotes (p. 7)
• 3. Biochemistry: A Prologue (p. 14)
• 4. Genetics: A Review (p. 19)
• 5. The Origin of Life (p. 28)
• 6. The Biochemical Literature (p. 34)
• Chapter 2 Aqueous Solutions (p. 39)
• 1. Properties of Water (p. 39)
• 2. Acids, Bases, and Buffers (p. 44)
• Chapter 3 Thermodynamic Principles: A Review (p. 51)
• 1. First Law of Thermodynamics: Energy Is Conserved (p. 52)
• 2. Second Law of Thermodynamics: The Universe Tends toward Maximum Disorder (p. 53)
• 3. Free Energy: The Indicator of Spontaneity (p. 56)
• 4. Chemical Equilibria (p. 57)
• Appendix Concentration Dependence of Free Energy (p. 60)
• Part II Biomolecules (p. 63)
• Chapter 4 Amino Acids (p. 65)
• 1. The Amino Acids of Proteins (p. 65)
• 2. Optical Activity (p. 71)
• 3. "Nonstandard" Amino Acids (p. 76)
• Chapter 5 Nucleic Acids, Gene Expression, and Recombinant DNA Technology (p. 80)
• 1. Nucleotides and Nucleic Acids (p. 80)
• 2. DNA Is the Carrier of Genetic Information (p. 82)
• 3. Double Helical DNA (p. 85)
• 4. Gene Expression and Replication: An Overview (p. 92)
• 5. Molecular Cloning (p. 101)
• Chapter 6 Techniques of Protein and Nucleic Acid Purification (p. 127)
• 1. Protein Isolation (p. 127)
• 2. Solubilities of Proteins (p. 131)
• 3. Chromatographic Separations (p. 133)
• 4. Electrophoresis (p. 144)
• 5. Ultracentrifugation (p. 151)
• 6. Nucleic Acid Fractionation (p. 155)
• Chapter 7 Covalent Structures of Proteins and Nucleic Acids (p. 161)
• 1. Primary Structure Determination of Proteins (p. 162)
• 2. Nucleic Acid Sequencing (p. 175)
• 3. Chemical Evolution (p. 182)
• 4. Bioinformatics: An Introduction (p. 191)
• 5. Chemical Synthesis of Polypeptides (p. 203)
• 6. Chemical Synthesis of Oligonucleotides (p. 207)
• Chapter 8 Three-Dimensional Structures of Proteins (p. 219)
• 1. Secondary Structure (p. 219)
• 2. Fibrous Proteins (p. 231)
• 3. Globular Proteins (p. 240)
• 4. Protein Stability (p. 258)
• 5. Quaternary Structure (p. 265)
• Appendix Viewing Stereo Pictures (p. 269)
• Chapter 9 Protein Folding, Dynamics, and Structural Evolution (p. 276)
• 1. Protein Folding: Theory and Experiment (p. 276)
• 2. Folding Accessory Proteins (p. 288)
• 3. Protein Structure Prediction and Design (p. 299)
• 4. Protein Dynamics (p. 302)
• 5. Conformational Diseases: Amyloids and Prions (p. 306)
• 6. Structural Evolution (p. 312)
• Chapter 10 Hemoglobin: Protein Function in Microcosm (p. 320)
• 1. Hemoglobin Function (p. 320)
• 2. Structure and Mechanism (p. 327)
• 3. Abnormal Hemoglobins (p. 339)
• 4. Allosteric Regulation (p. 345)
• Appendix Derivation of Symmetry Model Equations (p. 352)
• Chapter 11 Sugars and Polysaccharides (p. 356)
• 1. Monosaccharides (p. 356)
• 2. Polysaccharides (p. 362)
• 3. Glycoproteins (p. 369)
• Chapter 12 Lipids and Membranes (p. 382)
• 1. Lipid Classification (p. 382)
• 2. Properties of Lipid Aggregates (p. 389)
• 3. Biological Membranes (p. 394)
• 4. Membrane Assembly and protein Targeting (p. 414)
• 5. Lipoproteins (p. 439)
• Part III Mechanisms of Enzyme Action (p. 457)
• Chapter 13 Introduction to Enzymes (p. 459)
• 1. Historical Perspective (p. 459)
• 2. Substrate Specificity (p. 460)
• 3. Coenzymes (p. 463)
• 4. Regulation of Enzymatic Activity (p. 465)
• 5. A Primer of Enzyme Nomenclature (p. 470)
• Chapter 14 Rates of Enzymatic Reactions (p. 472)
• 1. Chemical Kinetics (p. 473)
• 2. Enzyme Kinetics (p. 477)
• 3. Inhibition (p. 482)
• 4. Effects of pH (p. 486)
• 5. Bisubstrate Reactions (p. 487)
• Appendix Derivations of Michaelis-Menten Equation Variants (p. 491)
• Chapter 15 Enzymatic Catalysis (p. 496)
• 1. Catalytic Mechanisms (p. 496)
• 2. Lysozyme (p. 507)
• 3. Serine Proteases (p. 515)
• 4. Drug Design (p. 528)
• Part IV Metabolism (p. 547)
• Chapter 16 Introduction to Metabolism (p. 549)
• 1. Metabolic Pathways (p. 549)
• 2. Organic Reaction Mechanisms (p. 552)
• 3. Experimental Approaches to the Study of Metabolism (p. 559)
• 4. Thermodynamics of Phosphate Compounds (p. 566)
• 5. Oxidation-Reduction Reactions (p. 571)
• 6. Thermodynamics of Life (p. 574)
• Chapter 17 Glycolysis (p. 581)
• 1. The Glycolytic Pathway (p. 582)
• 2. The Reactions of Glycolysis (p. 585)
• 3. Fermentation: The Anaerobic Fate of Pyruvate (p. 602)
• 4. Metabolic Regulation and Control (p. 607)
• 5. Metabolism of Hexoses Other than Glucose (p. 618)
• Chapter 18 Glycogen Metabolism (p. 626)
• 1. Glycogen Breakdown (p. 626)
• 2. Glycogen Synthesis (p. 632)
• 3. Control of Glycogen Metabolism (p. 635)
• 4. Glycogen Storage Diseases (p. 651)
• Chapter 19 Signal Transduction (p. 657)
• 1. Hormones (p. 657)
• 2. Heterotrimeric G Proteins (p. 673)
• 3. Tyrosine Kinase-Based Signaling (p. 683)
• 4. The Phosphoinositide Cascade (p. 707)
• Chapter 20 Transport through Membranes (p. 726)
• 1. Thermodynamics of Transport (p. 726)
• 2. Kinetics and Mechanisms of Transport (p. 727)
• 3. ATP-Driven Active Transport (p. 738)
• 4. Ion Gradient-Driven Active Transport (p. 746)
• 5. Neurotransmission (p. 750)
• Chapter 21 Citric Acid Cycle (p. 765)
• 1. Cycle Overview (p. 765)
• 2. Metabolic Sources of Acetyl-Coenzyme A (p. 768)
• 3. Enzymes of the Citric Acid Cycle (p. 781)
• 4. Regulation of the Citric Acid Cycle (p. 790)
• 5. The Amphibolic Nature of the Citric Acid Cycle (p. 792)
• Chapter 22 Electron Transport and Oxidative Phosphorylation (p. 797)
• 1. The Mitochondrion (p. 798)
• 2. Electron Transport (p. 802)
• 3. Oxidative Phosphorylation (p. 820)
• 4. Control of ATP Production (p. 836)
• Chapter 23 Other Pathways of Carbohydrate Metabolism (p. 843)
• 1. Gluconeogenesis (p. 843)
• 2. The Glyoxylate Cycle (p. 850)
• 3. Biosynthesis of Oligosaccharides and Glycoproteins (p. 852)
• 4. The Pentose Phosphate Pathway (p. 862)
• Chapter 24 Photosynthesis (p. 871)
• 1. Chloroplasts (p. 871)
• 2. Light Reactions (p. 873)
• 3. Dark Reactions (p. 896)
• Chapter 25 Lipid Metabolism (p. 909)
• 1. Lipid Digestion, Absorption, and Transport (p. 909)
• 2. Fatty Acid Oxidation (p. 914)
• 3. Ketone Bodies (p. 928)
• 4. Fatty Acid Biosynthesis (p. 930)
• 5. Regulation of Fatty Acid Metabolism (p. 940)
• 6. Cholesterol Metabolism (p. 942)
• 7. Eicosanoid Metabolism: Prostaglandins, Prostacyclins, Thromboxanes, Leukotrienes, and Lipoxins (p. 959)
• 8. Phospholipid and Glycolipid Metabolism (p. 969)
• Chapter 26 Amino Acid Metabolism (p. 985)
• 1. Amino Acid Deamination (p. 985)
• 2. The Urea Cycle (p. 991)
• 3. Metabolic Breakdown of Individual Amino Acids (p. 995)
• 4. Amino Acids as Biosynthetic Precursors (p. 1013)
• 5. Amino Acid Biosynthesis (p. 1030)
• 6. Nitrogen Fixation (p. 1044)
• Chapter 27 Energy Metabolism: Integration and Organ Specialization (p. 1054)
• 1. Major Pathways and Strategies of Energy Metabolism: A Summary (p. 1054)
• 2. Organ Specialization (p. 1057)
• 3. Metabolic Homeostasis: Regulation of Appetite, Energy Expenditure, and Body Weight (p. 1061)
• 4. Metabolic Adaptation (p. 1065)
• Chapter 28 Nucleotide Metabolism (p. 1069)
• 1. Synthesis of Purine Ribonucleotides (p. 1069)
• 2. Synthesis of Pyrimidine Ribonucleotides (p. 1076)
• 3. Formation of Deoxyribonucleotides (p. 1080)
• 4. Nucleotide Degradation (p. 1092)
• 5. Biosynthesis of Nucleotide Coenzymes (p. 1098)
• Part V Expression and Transmission of Genetic Information (p. 1105)
• Chapter 29 Nucleic Acid Structures (p. 1107)
• 1. Double Helical Structures (p. 1107)
• 2. Forces Stabilizing Nucleic Acid Structures (p. 1115)
• 3. Supercoiled DNA (p. 1122)
• Chapter 30 DNA Replication, Repair, and Recombination (p. 1136)
• 1. DNA Replication: An Overview (p. 1136)
• 2. Enzymes of Replication (p. 1139)
• 3. Prokaryotic Replication (p. 1152)
• 4. Eukaryotic Replication (p. 1162)
• 5. Repair of DNA (p. 1173)
• 6. Recombination and Mobile Genetic Elements (p. 1184)
• 7. DNA Methylation and Trinucleotide Repeat Expansions (p. 1204)
• Chapter 31 Transcription (p. 1216)
• 1. The Role of RNA in Protein Synthesis (p. 1216)
• 2. RNA Polymerase (p. 1221)
• 3. Control of Transcription in Prokaryotes (p. 1237)
• 4. Posttranscriptional Processing (p. 1254)
• Chapter 32 Translation (p. 1285)
• 1. The Genetic Code (p. 1285)
• 2. Transfer RNA and Its Aminoacylation (p. 1292)
• 3. Ribosomes and Polypeptide Synthesis (p. 1309)
• 4. Control of Eukaryotic Translation (p. 1342)
• 5. Posttranslational Modification (p. 1347)
• 6. Protein Degradation (p. 1352)
• Chapter 33 Viruses: Paradigms for Cellular Function (p. 1372)
• 1. Tobacco Mosaic Virus (p. 1374)
• 2. Icosahedral Viruses (p. 1379)
• 3. Bacteriophage [lambda] (p. 1390)
• 4. Influenza Virus (p. 1408)
• Chapter 34 Eukaryotic Gene Expression (p. 1422)
• 1. Chromosome Structure (p. 1422)
• 2. Genomic Organization (p. 1432)
• 3. Control of Expression (p. 1446)
• 4. Cell Differentiation and Growth (p. 1482)
• Chapter 35 Molecular Physiology
• 1. Blood Clotting
• 2. Immunity
• 3. Motility: Muscles, Cilia, and Flagella
• Index (p. 1527)

Author notes provided by Syndetics