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Hemostasis and thrombosis : basic principles and clinical practice / editors, Robert W. Colman ... [et al.].
Contributor(s): Colman, Robert W
.
Material type: 
BookPublisher: Philadelphia, PA : Lippincott Williams & Wilkins, 2006Edition: 5th ed.Description: xxiv, 1827 p. : ill. (some col.) ; 29 cm. + hbk.ISBN: 0781749964; 9780781749961.Subject(s): Blood coagulation disorders | Thrombosis | Blood -- Coagulation | HemostasisDDC classification: 616.157
| Item type | Current library | Call number | Copy number | Status | Barcode | |
|---|---|---|---|---|---|---|
| General lending | MTU Bishopstown Library Lending | 616.157 (Browse shelf(Opens below)) | 1 | Available | 00116307 |
Total holds: 0
Enhanced descriptions from Syndetics:
The pre-eminent reference on coagulation disorders is now in its thoroughly updated Fifth Edition. Written by more than 160 of the world's foremost authorities, this encyclopedic volume integrates basic science and clinical practice and details all that is currently known about blood clotting disorders and how to manage patients with these and related problems.
This edition has been reorganized into smaller, more tightly focused chapters to help readers find information easily. A new co-editor, Samuel Z. Goldhaber, MD, has expanded the cardiology portion of the book. Other new features include a two-color page design and more than 100 full-color illustrations.
Includes bibliographical references and index.
Table of contents provided by Syndetics
- Contributing Authors (p. v)
- Preface (p. xvii)
- Color Insert
- Part I Basic Principles of Hemostasis and Thrombosis
- 1 Overview of Hemostasis (p. 3)
- Section A Coagulation and its Regulation
- 2 Overview of Coagulation, Fibrinolysis, and Their Regulation (p. 17)
- 3 The Blood Coagulation Factors: Their Complementary DNAs, Genes, and Expression (p. 21)
- 4 Genetics of Coagulation (p. 59)
- 5 Tissue Factor Structure and Function (p. 91)
- 6 Contact Activation (Kallikrein-Kinin) Pathway: Multiple Physiologic and Pathophysiologic Activities (p. 107)
- 7 Molecular and Structural Biology of Factor IX (p. 131)
- 8 Factor VIII and Hemophilia A (p. 151)
- 9 Factor V (p. 177)
- 10 Thrombin (p. 193)
- 11 Protein Z and Protein Z-Dependent Protease Inhibitor (p. 215)
- 12 Factor XI (p. 221)
- 13 Antithrombin III and Heparin Cofactor II (p. 235)
- 14 Protein C, Protein S, and Thrombomodulin (p. 249)
- 15 Heparin and Vascular Proteoglycans (p. 271)
- Section B Fibrinolysis and Its Regulation (p. 285)
- 16 Fibrinogen Structure and Physiology (p. 285)
- 17 Factor XIII and Fibrin Stabilization (p. 317)
- 18 Plasminogen-Plasmin System (p. 335)
- 19 Plasminogen Activator Inhibitor-1 (p. 365)
- 20 Thrombin-Activatable Fibrinolysis Inhibitor aka Procarboxypeptidase U (p. 381)
- 21 [alpha]-Macroglobulins and Kunins (p. 395)
- 22 Human Endothelial Cell Plasmin-Generating System (p. 409)
- 23 Physiologic Regulation of Fibrinolysis (p. 419)
- Section C Platelet Structureand Function
- 24 Overview of Platelet Structure and Function (p. 437)
- 25 Platelet Production: Cellular and Molecular Regulation (p. 443)
- 26 Platelets: Structure Related to Function (p. 463)
- 27 Thrombopoietin (p. 483)
- 28 Platelet Glycoprotein Polymorphisms and Relationship to Function, Immunogenicity, and Disease (p. 493)
- 29 Molecular Mechanisms of Drug-Induced Thrombocytopenia (p. 507)
- 30 Integrin [alpha subscript IIb beta subscript 3] and Platelet Aggregation (p. 517)
- 31 The Platelet Glycoprotein Ib/IX/V Complex and Platelet Adhesion (p. 531)
- 32 Platelet Adenosine 5'-Diphosphate Receptors (p. 547)
- 33 Protease-Activated Receptors in Hemostasis, Thrombosis, and Vascular Biology (p. 555)
- 34 Platelet-Collagen Receptors (p. 567)
- 35 Platelet Prostanoid Receptors (p. 575)
- 36 Platelet Eicosanoids (p. 583)
- 37 Platelet and Megakaryocyte Lipids (p. 591)
- 38 Role of Platelets in Blood Coagulation (p. 605)
- 39 Platelet Signal Transduction (p. 617)
- Section D Vascular Biology, Embryogenesis, Development, and Disorders
- 40 Overview of Vascular Biology, Embryogenesis, Development, and Disorders (p. 631)
- 41 Development of the Vascular System (p. 633)
- 42 The Vascular Biology of Nitric Oxide and Nitric Oxide Synthases (p. 653)
- 43 Vascular Adaptations to Altered Blood Flow (p. 667)
- 44 Angiogenesis, Lymphangiogenesis, and Vascular Morphogenesis (p. 679)
- 45 Monocyte-Platelet-Endothelial Interactions (p. 691)
- 46 Structure and Function of von Willebrand Factor
- 47 Platelet-Vessel Wall Interactions in Flowing Blood (p. 723)
- 48 Rheology of Thrombosis (p. 737)
- 49 Biomaterial-Associated Thrombosis (p. 751)
- 50 The Vascular Response to Injury (p. 761)
- 51 Vessel Wall Lipids (p. 769)
- 52 Thrombophilia Genetics (p. 779)
- 53 Inflammation and Atherothrombosis (p. 795)
- 54 Histopathology of Atherosclerosis (p. 813)
- 55 Laboratory Markers of Platelet Activation (p. 825)
- 56 Laboratory Markers of Coagulation and Fibrinolysis (p. 835)
- 57 Malignancy and Hemostasis (p. 851)
- Part II Clinical Applications
- Section A Inherited Hemorrhagic Disorders
- 58 Overview of Inherited Hemorrhagic Disorders (p. 877)
- 59 Clinical Manifestations and Therapy of the Hemophilias (p. 887)
- 60 von Willebrand Disease: Diagnosis, Classification, and Treatment (p. 905)
- 61 Inherited Disorders of Prothrombin Conversion (p. 923)
- 62 Afibrinogenemias and Dysfibrinogenemias (p. 939)
- 63 Familial Multiple Coagulation Factor Deficiencies (p. 953)
- 64 Hereditary Disorders of Platelet Secretion and Signal Transduction (p. 961)
- 65 Inherited Thrombocytopenias (p. 975)
- 66 Inherited Abnormalities of the Platelet Membrane: Glanzmann Thrombasthenia, Bernard-Soulier Syndrome, and Other Disorders (p. 987)
- 67 Primary Vascular Disorders (p. 1011)
- Section B Acquired Hemorrhagic Disorders
- 68 Hemostatic Abnormalities in Liver Disease (p. 1025)
- 69 Clinical Disorders of Fibrinolysis (p. 1035)
- 70 Acquired Qualitative Platelet Defects (p. 1045)
- 71 Acquired Disorders of Coagulation: The Immune Coagulopathies (p. 1061)
- 72 Immune Thrombocytopenic Purpura (p. 1085)
- 73 Drug-Induced Thrombocytopenia (p. 1095)
- 74 Hemostatic Problems in Surgical Patients (p. 1103)
- 75 Obstetric Hemorrhage (p. 1121)
- 76 Please note: A finalized version of Chapter 76 (pages 1129 through 1146) was not available at press time for inclusion in the book
- Section C Therapy of Bleeding Disorders
- 77 Clinical Approach to the Bleeding Patient (p. 1147)
- 78 Management of Acute Hemorrhage (p. 1159)
- 79 Therapy with Antifibrinolytic Agents (p. 1173)
- 80 Transfusion Medicine Platelet Transfusion Therapy, Plasma, and Plasma Concentrates (p. 1193)
- 81 New Approaches for the Therapy of Bleeding Disorders, Including Gene Therapy (p. 1205)
- Section D Venous Thromboembolic Disorders
- 82 Overview of Venous Thromboembolism (p. 1219)
- 83 Epidemiology of Venous Thromboembolism (p. 1227)
- 84 Women's Health and Venous Thromboembolism (p. 1235)
- 85 Cancer and Thrombosis (p. 1251)
- 86 Venous Thrombosis in Unusual Sites (p. 1263)
- Part I Upper Extremity Deep Vein Thrombosis
- Part II Cranial and Abdominal Venous Thrombosis
- 87 Diagnosis of Venous Thromboembolism (p. 1279)
- 88 Risk Stratification in Patients with Pulmonary Embolism (p. 1299)
- 89 Treatment of Venous Thromboembolism (p. 1307)
- 90 Thrombolysis in Venous Thromboembolic Disease (p. 1317)
- 91 Mechanical Devices and Embolectomy (p. 1331)
- 92 Chronic Thromboembolic Pulmonary Hypertension (p. 1339)
- 93 Paradoxical Embolism (p. 1351)
- 94 Prevention of Venous Thromboembolism in General Surgery (p. 1361)
- 95 Prevention of Venous Thromboembolism in Orthopedic Surgery (p. 1369)
- 96 Venous Thromboprophylaxis in Medical Patients (p. 1381)
- Section E Cardiovascularthrombotic Diseases
- 97 Acute Coronary Syndromes (p. 1387)
- 98 Antithrombotic Therapy for Percutaneous Coronary Intervention (p. 1405)
- 99 Coronary Bypass Grafting and Cardiac Surgery (p. 1433)
- 100 Medical Therapy for Peripheral Arterial Disease (p. 1441)
- 101 Surgery for Peripheral Arterial Disease (p. 1453)
- 102 Prevention and Treatment of Acute Stroke (p. 1477)
- 103 Interdisciplinary Management of Acute Stroke (p. 1497)
- 104 Antithrombotic Therapy for Patients with Atrial Fibrillation (p. 1517)
- 105 Advanced Cardiomyopathy and Surgery (p. 1529)
- 106 Valvular Heart Disease (p. 1539)
- 107 Overview of Complex Thrombohemorrhagic Disorders (p. 1553)
- Section F Complex Thrombohemorrhagic Disorders
- 108 Myeloproliferative Disorders and Thrombohemorrhagic Complications (p. 1557)
- 109 Consumptive Thrombohemorrhagic Disorders (p. 1571)
- 110 Coagulation Abnormalities in Sepsis (p. 1601)
- 111 Thrombotic Thrombocytopenic Purpura-Hemolytic Uremic Syndrome (p. 1613)
- 112 Antiphospholipid Antibodies and the Antiphospholipid Syndrome (p. 1621)
- 113 Thrombosis in Infancy and Childhood (p. 1637)
- 114 Heparin-Induced Thrombocytopenia (p. 1649)
- 115 Coumarin-Induced Skin Necrosis and Venous Limb Gangrene (p. 1663)
- Section G Therapy, New Directions, and Complications in Thrombotic Disorders
- 116 Anticoagulant Therapy for Major Arterial and Venous Thromboembolism (p. 1673)
- 117 Anticoagulation Clinics (p. 1689)
- 118 Drug Interactions with Oral Anticoagulants (p. 1699)
- 119 Hemorrhagic Complications of Anticoagulation (p. 1707)
- 120 Antiplatelet Therapy (p. 1725)
- 121 Foundations of Thrombolytic Therapy (p. 1739)
- 122 New Thrombolytic Agents (p. 1753)
- 123 New Antithrombotic Drugs (p. 1763)