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GC/MS : a practical user's guide / Marvin C. McMaster.

By: McMaster, Marvin C.
Material type: materialTypeLabelBookPublisher: Hoboken, N.J. : Wiley-Interscience, 2008Edition: 2nd ed.Description: xii, 180 p. : ill. ; 25 cm.ISBN: 9780470101636 ; 0470101636 .Subject(s): Gas chromatography | Mass spectrometryDDC classification: 543.85
Contents:
Part I: A GC/MS Primer -- Introduction -- Sample preparation and introduction -- The gas chromatograph -- The mass spectrometer -- Getting started in GC/MS -- Part II: A GC/MS optimization -- Chromatographic methods development -- Mass spectrometer setup and operation -- Data processing and network interfacing -- System maintenance and troubleshooting -- Part III: Specific applications of GC/MS -- GC/MS in the environmental laboratory -- GC/MS in forensics, toxicology, and space science -- An introduction to structural interpretation -- Ion trap GC/MS systems -- Other GC/MS systems -- An introduction to LC/MS -- Innovation in GC/MS.
Holdings
Item type Current library Call number Copy number Status Barcode
General lending MTU Bishopstown Library Lending 543.85 (Browse shelf(Opens below)) 1 Available 00169568
Total holds: 0

Enhanced descriptions from Syndetics:

Updated and expanded, the classic guide to GC/MS helps chromatographers quickly learn to use this technique for analyzing and identifying compounds. After explaining the fundamentals, it discusses optimizing, tuning, using, and maintaining GC/MS equipment; explores advances in miniaturized and field-portable GC/MS systems and microfluidic components; and more. Complete with a CD-ROM, it covers applications in the environmental laboratory and in forensics, toxicology, and space science. This is the premier resource for professionals in those fields and for students.

Includes bibliographical references (pages 173-174) and index.

Part I: A GC/MS Primer -- Introduction -- Sample preparation and introduction -- The gas chromatograph -- The mass spectrometer -- Getting started in GC/MS -- Part II: A GC/MS optimization -- Chromatographic methods development -- Mass spectrometer setup and operation -- Data processing and network interfacing -- System maintenance and troubleshooting -- Part III: Specific applications of GC/MS -- GC/MS in the environmental laboratory -- GC/MS in forensics, toxicology, and space science -- An introduction to structural interpretation -- Ion trap GC/MS systems -- Other GC/MS systems -- An introduction to LC/MS -- Innovation in GC/MS.

CIT Module CHEA 8001- Supplementary reading

Table of contents provided by Syndetics

  • Preface (p. xi)
  • Part I A GC/MS Primer (p. 1)
  • 1 Introduction (p. 3)
  • 1.1 Why Use GC/MS? (p. 4)
  • 1.2 Interpretation of Fragmentation Data Versus Spectral Library Searching (p. 5)
  • 1.3 The Gas Chromatograph/Mass Spectrometer (p. 6)
  • 1.4 Systems and Costs (p. 15)
  • 1.5 Competitive Analytical Systems (p. 17)
  • 2 Sample Preparation and Introduction (p. 21)
  • 2.1 Direct Sample Injection into the Mass Spectrometer (p. 22)
  • 2.2 Sample Purification (p. 23)
  • 2.3 Manual GC Injection (p. 25)
  • 2.4 Automated GC/MS Injection (p. 27)
  • 3 The Gas Chromatography (p. 29)
  • 3.1 The GC Oven and Temperature Control (p. 29)
  • 3.2 Selecting GC Columns (p. 30)
  • 3.3 Separation Parameters and Resolution (p. 32)
  • 3.4 GC Control Variables (p. 34)
  • 3.5 Derivatives (p. 36)
  • 4 The Mass Spectrometer (p. 37)
  • 4.1 Vacuum Pumps (p. 37)
  • 4.2 Interfaces and Sources (p. 40)
  • 4.3 Quadrupole Operation (p. 43)
  • 4.4 The Ion Detector (p. 45)
  • 5 Getting Started in GC/MS (p. 47)
  • 5.1 Mode Selection (p. 47)
  • 5.2 Setting Up (p. 48)
  • 5.3 Mass Spectrometer Tuning and Calibration (p. 50)
  • 5.4 Sample Injection and Chromatographic Separation (p. 52)
  • 5.5 Data Collection Processing (p. 52)
  • Part II A GC/MS Optimization (p. 57)
  • 6 Chromatographic Methods Development (p. 59)
  • 6.1 Isothermal Operation (p. 60)
  • 6.2 Linear Temperature Gradients (p. 61)
  • 6.3 Assisted Re-Equilibration (p. 61)
  • 6.4 Hinge Point Gradient Modification (p. 62)
  • 6.5 Pressure Gradient Development (p. 63)
  • 6.6 Column Replacement (p. 64)
  • 7 Mass Spectrometer Setup and Operation (p. 67)
  • 7.1 Mass Spectrometer Calibration with Calibration Gases (p. 67)
  • 7.2 Mass Axis Tuning (p. 69)
  • 7.3 System Tuning for Environmental Analysis (p. 71)
  • 7.4 Acquiring Information (p. 73)
  • 7.5 Data Displays and Library Searches (p. 75)
  • 8 Data Processing and Network Interfacing (p. 77)
  • 8.1 Peak Identification and Integration (p. 77)
  • 8.2 Multi-Instrument Control (p. 79)
  • 8.3 Networking Connection (p. 80)
  • 8.4 Replacement Control and Processing Systems (p. 80)
  • 8.5 File Conversion and Data File Exchange (p. 81)
  • 8.6 Data Re-Entry and Transcription Errors (p. 83)
  • 9 System Maintenance and Troubleshooting (p. 85)
  • 9.1 Gas Chromatograph Maintenance (p. 85)
  • 9.2 Mass Spectrometer Maintenance (p. 87)
  • 9.3 System Electrical Grounding (p. 92)
  • Part III Specific Applications of GC/MS (p. 93)
  • 10 GC/MS in The Environmental Laboratory (p. 95)
  • 10.1 Volatile Organic Analysis: EPA Method 624 (p. 96)
  • 10.2 SemiVolatile Organic Analysis: EPA Method 625 (p. 100)
  • 10.3 EPA and State Reporting Requirements (p. 105)
  • 11 GC/MS in Forensics, Toxicology, and Space Science (p. 109)
  • 11.1 Forensic Analysis (p. 110)
  • 11.2 Clinical Drug Analysis (p. 110)
  • 11.3 Arson and Security Analysis (p. 111)
  • 11.4 Astrochemistry (p. 111)
  • 12 An Introduction to Structural Interpretation (p. 113)
  • 12.1 History of the Sample (p. 115)
  • 12.2 Elemental Composition (p. 116)
  • 12.3 Search for Logical Fragmentation Intervals (p. 118)
  • 13 Ion Trap GC/MS Systems (p. 119)
  • 13.1 Ion Trap Components (p. 120)
  • 13.2 Ion Trap Operation (p. 120)
  • 13.3 The Linear Ion Trap Analyzer (p. 124)
  • 13.4 Ion Traps in the Environmental Laboratory (p. 125)
  • 13.5 Chemical Ionization in the Ion Trap (p. 125)
  • 13.6 Ion Trap GC/MS/MS (p. 125)
  • 14 Other GC/MS Systems (p. 127)
  • 14.1 Sequential Mass Spectrometry (Triple-Quadrupole or Tandem GC/MS) (p. 128)
  • 14.2 Magnetic Sector Systems (p. 130)
  • 14.3 Laser Time-of-Flight (GC/TOF-MS) GC/MS Systems (p. 132)
  • 14.4 Fourier Transform (GC/FT-MS) GC/MS Systems (p. 133)
  • 15 An Introduction to LC/MS (p. 137)
  • 15.1 Liquid Interfacing into the Mass Spectrometer (p. 138)
  • 15.2 Electrospray and Nano-Spray LC/MS (p. 139)
  • 15.3 Ion Spray LC/MS (p. 140)
  • 15.4 LC/MS/MS (p. 142)
  • 15.5 LC/MS Versus GC/MS (p. 142)
  • 16 Innovation in GC/MS (p. 145)
  • 16.1 Microfludics in GC/MS (p. 146)
  • 16.2 Resistance Column Heating (p. 147)
  • 16.3 Portable Gas Supply (p. 147)
  • 16.4 Portable GC/MS Systems (p. 147)
  • 16.5 New Column Technology (p. 148)
  • Appendix A GC/MS Frequently Asked Questions (p. 151)
  • A.1 GC FAQs (p. 151)
  • A.2 Column FAQs (p. 153)
  • A.3 MS FAQs (p. 153)
  • A.4 GC/MS FAQs (p. 155)
  • Appendix B GC/MS Troubleshooting Quick Reference (p. 159)
  • B.1 GC Injector Problems (p. 159)
  • B.2 GC Column Problems (p. 160)
  • B.3 MS Vacuum and Power Problems (p. 162)
  • B.4 MS Source and Calibration Problems (p. 163)
  • B.5 MS Sensitivity and Detector Problems (p. 164)
  • Appendix C Sources of GC/MS Background Contamination (p. 165)
  • Appendix D A Glossary of GC/MS Terms (p. 167)
  • Appendix E GC/MS Selected Reading List (p. 173)
  • E.1 Journals (p. 173)
  • E.2 Books (p. 173)
  • Index (p. 175)

Author notes provided by Syndetics

Marvin C. McMaster is a consultant and adjunct professor of chemistry at the University of Missouri-St. Louis, teaching courses on HPLC, GC/MS, LC/MS, and laboratory computing.