Introduction to toxicology [electronic book] / John Timbrell.
By: Timbrell, John A [author]
.
Material type: 
BookPublisher: London ; New York : Taylor & Francis, 2002Copyright date: ©2002 Edition: Third edition.Description: online resource (ix, 215 pages) : illustrations.Content type: text Media type: computer Carrier type: online resourceISBN: 0415247632 (paperback); 9780203361399 (e-book); 9781000026962 (e-book).Subject(s): ToxicologyAdditional physical formats: Print version: Introduction to toxicologyDDC classification: 615.9 Online resources: Access eBook Also available in print form.Summary: This third edition of Introduction to Toxicology caters for this need in a clear and easy-to-read style, featuring up-to-the-minute information, relevant toxicological examples that reinforce principles, end-of-chapter essay questions, new and redrawn illustrations, glossary of terms, and extensively revised bibliography. The book describes the fundamental principles of absorption, distribution, metabolism and excretion, as well as the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.
| Item type | Current library | Call number | Status | Notes | |
|---|---|---|---|---|---|
| eBook | MTU Online eBook | 615.9 (Browse shelf(Opens below)) | Available | MTU Cork Module BIOL8007 - Core reading, MTU CORK Module BIOL 8009 - Core reading, MTU CORK Module CHEM 7003 - Core reading. |
Enhanced descriptions from Syndetics:
Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing.
This third edition caters for this need in a clear and easy-to-read style, featuring:
* Up-to-the-minute information
* Relevant toxicological examples that reinforce principles
* End-of-chapter essay questions
* New and redrawn illustrations
* Glossary of terms
* Extensively revised bibliography
The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.
Includes bibliographical references and index.
This third edition of Introduction to Toxicology caters for this need in a clear and easy-to-read style, featuring up-to-the-minute information, relevant toxicological examples that reinforce principles, end-of-chapter essay questions, new and redrawn illustrations, glossary of terms, and extensively revised bibliography. The book describes the fundamental principles of absorption, distribution, metabolism and excretion, as well as the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.
CIT Module BIOL 8007 - Core reading.
CIT Module BIOL 8009 - Core reading.
CIT Module CHEM 7003 - Core reading.
Also available in print form.
Electronic reproduction.: Dawson Books. Mode of access: World Wide Web.
Electronic reproduction.: ProQuest Central. Mode of access: World Wide Web.
Table of contents provided by Syndetics
- Preface to the First Edition (p. xi)
- Preface to the Third Edition (p. xii)
- Chapter 1 Introduction (p. 1)
- Chapter outline (p. 1)
- Historical aspects (p. 2)
- Types of toxic substance (p. 5)
- Types of exposure (p. 8)
- Dose-response relationship (p. 9)
- Summary and learning objectives (p. 15)
- Questions (p. 16)
- Bibliography (p. 17)
- Chapter 2 Disposition of Toxic compounds (p. 19)
- Chapter outline (p. 19)
- Absorption of toxic compounds (p. 20)
- Distribution of toxic compounds (p. 27)
- Excretion of toxic compounds (p. 30)
- Summary and learning objectives (p. 34)
- Questions (p. 35)
- Bibliography (p. 37)
- Chapter 3 Metabolism of Foreign Compounds (p. 39)
- Chapter outline (p. 39)
- Introduction (p. 39)
- Factors affecting toxic responses (p. 48)
- Summary and learning objectives (p. 52)
- Questions (p. 53)
- Bibliography (p. 54)
- Chapter 4 Types of Exposure and Response (p. 57)
- Chapter outline (p. 57)
- Types of exposure (p. 57)
- Route of exposure (p. 58)
- Types of toxic response (p. 58)
- Biomarkers (p. 67)
- Summary and learning objectives (p. 68)
- Questions (p. 70)
- Bibliography (p. 71)
- Chapter 5 Drugs as Toxic Substances (p. 73)
- Chapter outline (p. 73)
- Introduction (p. 73)
- Paracetamol (p. 74)
- Aspirin (salicylate) (p. 75)
- Hydralazine (p. 78)
- Halothane (p. 80)
- Debrisoquine (p. 81)
- Thalidomide (p. 82)
- Drug interactions (p. 83)
- Altered responsiveness: glucose-6-phosphate dehydrogenase deficiency (p. 84)
- Summary and learning objectives (p. 85)
- Questions (p. 86)
- Bibliography (p. 86)
- Chapter 6 Industrial Toxicology (p. 89)
- Chapter outline (p. 89)
- Industrial chemicals (p. 89)
- Means of exposure (p. 90)
- Toxic effects (p. 90)
- Vinyl chloride (p. 91)
- Cadmium (p. 92)
- Aromatic amines (p. 93)
- Asbestos (p. 94)
- Legislation (p. 95)
- Summary and learning objectives (p. 96)
- Questions (p. 97)
- Bibliography (p. 98)
- Chapter 7 Food Additives and Contaminants (p. 99)
- Chapter outline (p. 99)
- Introduction (p. 99)
- Tartrazine (p. 101)
- Saccharin (p. 102)
- Food contaminants (p. 103)
- Summary and learning objectives (p. 106)
- Questions (p. 106)
- Bibliography (p. 107)
- Chapter 8 Pesticides (p. 109)
- Chapter outline (p. 109)
- Introduction (p. 109)
- DDT (p. 111)
- Organophosphorus compounds (p. 114)
- Paraquat (p. 116)
- Fluoroacetate (p. 118)
- Summary and learning objectives (p. 118)
- Questions (p. 119)
- Bibliography (p. 119)
- Chapter 9 Environmental Pollutants (p. 121)
- Chapter outline (p. 121)
- Introduction (p. 121)
- Air pollution (p. 122)
- Particulates (p. 125)
- Acid rain (p. 125)
- Lead pollution (p. 128)
- Water pollution (p. 130)
- Arsenic (p. 131)
- Food chains (p. 132)
- Endocrine disruptors (p. 134)
- Mercury and methylmercury (p. 137)
- Summary and learning objectives (p. 140)
- Questions (p. 141)
- Bibliography (p. 142)
- Chapter 10 Natural Products (p. 143)
- Chapter outline (p. 143)
- Plant toxins (p. 144)
- Animal toxins (p. 146)
- Fungal toxins (p. 148)
- Microbial toxins (p. 148)
- Summary and learning objectives (p. 149)
- Questions (p. 150)
- Bibliography (p. 150)
- Chapter 11 Household Products (p. 151)
- Chapter outline (p. 151)
- Introduction (p. 151)
- Carbon monoxide (p. 152)
- Antifreeze: ethylene glycol (p. 154)
- Cyanide (p. 155)
- Alcohol (p. 156)
- Glue sniffing and solvent abuse (p. 157)
- Antidotes and the treatment of poisoning (p. 157)
- Summary and learning objectives (p. 159)
- Questions (p. 160)
- Bibliography (p. 161)
- Chapter 12 Toxicity Testing and Risk Assessment (p. 163)
- Chapter outline (p. 163)
- Introduction (p. 163)
- Evaluation of toxicity (p. 164)
- Acute toxicity tests (p. 167)
- Sub-acute toxicity tests (p. 168)
- Chronic toxicity tests (p. 169)
- Testing in vitro (p. 171)
- Risk assessment and interpretation of toxicological data (p. 173)
- Conclusions (p. 179)
- Summary and learning objectives (p. 180)
- Questions (p. 181)
- Bibliography (p. 181)
- Answers to questions (p. 183)
- Glossary (p. 197)
- Index (p. 207)