Protecting group chemistry / Jeremy Robertson.
By: Robertson, Jeremy
.
Material type: 
BookSeries: Oxford chemistry primers ; 95.Publisher: Oxford New York : Oxford University Press, 2000Description: 96 p. : ill. ; 25 cm. + pbk.Content type: text Media type: unmediated Carrier type: volumeISBN: 0198502753; 9780198502753.Subject(s): Organic compounds -- Synthesis | Protective groups (Chemistry) | Inorganic chemistry | Physical chemistryDDC classification: 547.2 ROB Summary: Provides an overview of methods that allow specific sites within an organic molecule to be manipulated without affecting other sites. This book emphasises the link between the mechanisms of organic chemistry and the choice of specific protecting groups that block chemical reactivity at those sites that must remain unaffected.
| Item type | Current library | Call number | Copy number | Status | Barcode | |
|---|---|---|---|---|---|---|
| General lending | MTU Kerry North Campus Library First Floor Main | 547.2 ROB (Browse shelf(Opens below)) | 1 | Available | 38888000054332 |
Enhanced descriptions from Syndetics:
Protecting Group Chemistry provides an overview of the general methods that are used to block the reactivity of - i.e. protect - specific functional grops thus allowing others, present within the same molecule, to be manipulated unambiguously. An introductory chapter outlines protecting group strategy, relevant aspects of functional group reactivity, temporary protection, and introduces the concept of protecting group devices as an aid to unifying the wide range of available methods. The rest of the book is divided on the basis of broad classes of the experimental conditions that lead to cleavage of each protecting group (acid/electrophile, base/nucleophile, oxidising or reducing agent). The treatment differs from traditional texts in that it places the emphasis on making a connection between the fundamental mechanisms of organic chemsitry - ionisation, substitution, addition, elimination, oxidation and reduction, etc. - and how a particular protecting group can best be selected in a given situation.
Includes index.
Includes bibliographical references and index.
Provides an overview of methods that allow specific sites within an organic molecule to be manipulated without affecting other sites. This book emphasises the link between the mechanisms of organic chemistry and the choice of specific protecting groups that block chemical reactivity at those sites that must remain unaffected.
Table of contents provided by Syndetics
- 1 Introduction
- 2 Acid-labile protecting groups
- 3 Nucleophile/base-labile protecting groups
- 4 Silyl protecting groups
- 5 Redox deprotection
- Index