Bacteriophage : genetics and molecular biology / edited by Stephen Mc Grath and Douwe van Sinderen.
Contributor(s): Mc Grath, Stephen
| Sinderen, Douwe van
.
Material type:
BookPublisher: Norfolk, UK : Caister Academic Press, 2007Description: viii, 343, A-1 p. : ill. ; 24 cm. + hbk.ISBN: 9781904455141 .Subject(s): Bacteriophages| Item type | Current library | Call number | Copy number | Status | Barcode | |
|---|---|---|---|---|---|---|
| General lending | MTU Bishopstown Library Lending | 579.26 (Browse shelf(Opens below)) | 1 | Available | 00132096 |
Enhanced descriptions from Syndetics:
Bacteriophages (viruses that infect bacteria) are fascinating organisms that have played and continue to play a key role in bacterial genetics and molecular biology. Phage can confer key phenotypes on their host - for example, converting a non-pathogenic strain into a pathogen - and they play a key role in regulating bacterial populations in all sorts of environments. The phage-bacterium relationship varies enormously, from the simple predator-prey model to a complex, almost symbiotic relationship that promotes the survival and evolutionary success of both. While infection of bacteria used in the fermentation industry can be very problematic and result in financial losses, in other scenarios, phage infection of bacteria can be exploited for industrial and/or medical applications. Interest in phage and phage gene products as potential therapeutic agents is increasing rapidly and is likely to have a profound impact on the pharmaceutical industry and biotechnology in general over the coming years. One potential application is the use of phage to combat the growing menace of antibiotic-resistant infections. Written by eminent international researchers actively involved in the disparate areas of bacteriophage research, this book focuses on the current rapid developments in this exciting field. The book opens with an excellent chapter that provides a broad overview of the topics and also highlights the multifaceted nature of bacteriophage research. This is followed by a series of reviews that focus on the current, most cutting-edge topics including bioinformatics and genomics, phage in the environment, bacteriophage in medicine, transfer of phage DNA to the host, contribution to host phenotype, and much more. The book will be essential reading for all phage researchers and of interest to molecular biologists and microbiologists working on bacteria in academia, biotechnology, and pharmaceutical companies, as well as in the food industry.
Includes bibliographical references and index.
The new phage biology: from genomics to applications / Olivia McAuliffe, R. Paul Ross and Gerald F. Fitzgerald -- Bacteriophage bioinformatics and genomics / Carlos A. Canchaya, Marco Ventura and Douwe van Sinderen -- Bacteriophage in the environment / Markus G. Weinbauer, Martin Agis, Osana Bonilla-Findji, Andrea Malits and Christian Winter -- Bacteriophages and food fermentations / Eric Emond and Sylvain Moineau -- Bacteriophages in medicine / Andrzej Gorski, Jan Borysowski, Ryszard Miedzybrodzki and Beata-Weber-Dabrowska -- Phage therapy: the western perspective / Harald Brussow -- Bacteriophage - host interaction in lactic acid bacteria / Christina Skovgaard Vegge, John Gerard Kenny, Lone Brondsted, Stephen McGrath and Douwe van Sinderen -- Transfer of DNA from phage to host / Lucienne Letellier, Laure Plancon and Pascale Boulanger -- Prophages and their contribution to host cell phenotype / W. Michael McShan and Joseph J. Ferretti -- Prophage induction of phage / John W. Little -- Phage o29: membrane-associated DNA replication and mechanism of alternative infection strategy / Wilfried J. J. Meijer, Daniel Munoz-Espin, Virginia Castilla-Llorente and Margarita Salas -- Release of progeny phages from infected cells / Carlos Sao-Jose, Joao G. Nascimento, Ricardo Parreira and Mario A. Santos.